Turmeric Supports Kidney Function

The antioxidant spice turmeric (Curcuma longa) supports kidney function in individuals with suboptimal blood sugar metabolism, according to a recent study. Kidney function is related to healthy blood sugar metabolism. Previous research suggested that this may be related to the protein, transforming growth factor-beta (TGF-beta), which plays a role in the cell cycle and programmed cell death (apoptosis). Also, the pro-inflammatory molecules interleukin (IL)-8 and tumor necrosis factor-alpha (TNF-alpha), may also be involved. Kidney function can be monitored by evaluating the amount of protein excreted into the urine.

In this randomized, double-blind and placebo-controlled study, 40 subjects with suboptimal blood sugar metabolism and kidney function were included. The subjects received either 500 mg turmeric three times daily or a placebo for 2 months. The subjects were assessed for serum levels of TGF-beta and IL-8 and urinary protein excretion at the beginning of the study and again after 2 months of supplementation.

The study found that supplementation with turmeric significantly decreased serum levels of TGF-beta and IL-8 and urinary protein excretion compared to levels at the beginning of the study. No adverse effects related to turmeric supplementation were observed.

The study results showed that short-term turmeric supplementation can enhance several parameters of kidney function.

Reference:

Khajehdehi P, Pakfetrat M, Javidnia K, Azad F, Malekmakan L, Nasab MH, Dehghanzadeh G. Oral supplementation of turmeric attenuates proteinuria, transforming growth factor-b and interleukin-8 levels in patients with overt type 2 diabetic nephropathy: A randomized, double-blind and placebo-controlled study. Scand J Urol Nephrol. 2011 May 31. Published Online Ahead of Print.