Selenium Enhances Prostate Health

The latest research indicates that selenium improves markers of prostate health. Selenium is a trace mineral that is incorporated into proteins known as selenoproteins, which function as antioxidant enzymes. These selenoproteins help prevent cellular damage from free radicals.

Thirty healthy middle-aged men were supplemented with 200 mcg of selenium and an additional 30 men received a placebo for 6 weeks. The subjects were evaluated for levels of erythrocyte (red blood cell) and plasma glutathione peroxidase, which is an important antioxidant enzyme. Previous research has shown that small changes in the activity of blood glutathione peroxidase can reflect larger changes in the prostate. The subjects were also assessed for levels of plasma prostate-specific antigen (PSA), which is frequently used as a screening assessment of prostate health. PSA is a protein made by cells in the prostate gland and is measured in the blood. PSA levels can rise with problems related to the prostate.

The results of the study indicated that selenium supplementation increased activity of erythrocyte and plasma glutathione peroxidase. Furthermore, selenium supplementation resulted in decreased levels of plasma PSA. These changes were not seen in the placebo group.

The study authors stated, “In conclusion, this study suggests that US middle-aged men may not typically consume optimal amounts of selenium.”

Reference:

Zhang W, Joseph E, Hitchcock C, DiSilvestro RA. Selenium glycinate supplementation increases blood glutathione peroxidase activities and decreases prostate-specific antigen readings in middle-aged US men. Nutr Res. 2011 Feb 12. Published Online Ahead of Print.