New And Improved Support In Your Fight Against Free Radicals
When it comes to free radicals, you can run, but you can’t hide—at least, not unless you want to stop exercising, eating and breathing. Close encounters with these rogue molecules are inevitable especially as your natural antioxidant defenses decline with age… leaving your body lacking both the energy and resources it needs to support itself against oxidative stress.
That’s why furnishing your body with a full spectrum of free radical-quenching antioxidants may be the single most important way to keep your body at the top of its game. And it’s with this goal in mind that CP has revamped its comprehensive daily formula, Complete Antioxidant (available after November 15).
So what exactly will you find in this new and improved daily supplement?
For starters, there’s R-lipoic acid—a mitochondrial coenzyme that can assist in revitalizing your body’s stores of multiple antioxidants. Animal studies have shown that this natural compound can revitalize age-related metabolic declines, while supporting oxygen consumption, curbing lipid peroxidation and restoring essential levels of beneficial glutathione and ascorbic acid in liver cells.1
Meanwhile, the flavonol myricetin has been shown to have significant antioxidant activity, being able to inhibit markers of lipid peroxidation and enhance DNA integrity in rat and human liver cells, respectively.2-3 Studies show that myricetin plays a key role in optimal cellular function, and that it also enhances prostate health and supports healthy blood sugar metabolism.4-5
N-acetyl cysteine (NAC) is known for its role in healthy liver and lung function—but like R-lipoic acid, it also stimulates the generation of glutathione, one of the most critical antioxidants in your body.6-7 So it’s no surprise that research shows that NAC is able to balance inflammatory responses and curb oxidative stress after high intensity exercise, which is known to create a boost in free radicals.8
Other key nutrients in this redesigned formula include astaxanthin—an antioxidant carotenoid that research suggests can support heart health, with studies showing a notable reduction in lipid peroxidation within just three months of supplementation.9-10 A subcategory of vitamin E known as tocotrienols delivers equally impressive benefits when it comes to cholesterol metabolism—not to mention brain health, as tocotrienols have been shown to support neurons against the effects of toxin exposure.11-12
Finally, the free radical-scavenging botanicals Rhodiola rosea and rosemary offer essential plant-based antioxidant support. Rhodiola rosea is a powerful adaptogen, which balances inflammatory responses, supports heart health, and assists your immune system—while rosemary furnishes your body with beneficial substances that help to keep both inflammatory responses and blood sugar metabolism in check.13-15
New-and-improved Complete Antioxidant combines all of the botanicals and nutrients above with the well known antioxidant vitamins C, E and A, making for a complete daily arsenal of free radical-fighting support—and it’s available from Complementary Prescriptions™.
References:
1. Hagen, TM, Ingersoll RT, Lykkesfeldt J, Liu J, Wehr CM, Vinarsky V, Bartholomew JC, Ames BN. (R)-a-Lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate. FASEB J. 1999;13:411-418.
2. Ong KC, Khoo HE. Biological Effects of Myricetin Gen. Pharmac. 1997;29(2):121-126.
3. Delgado ME, Haza AI, Arranz N, Garcîa A, Morales P. Dietary polyphenols protect against N-nitrosamines and benzo(a)pyrene induced DNA damage (strand breaks and oxidized purines/pyrimidines) in HepG2 human hepatoma cell. Eur J Nutr (2008) 47:479-490.
4. Kyoung Ah Kang, Zhi Hong Wang, Rui Zhang, Mei Jing Piao, Ki Cheon Kim, Sam Sik Kang, Young Woo Kim, Jongsung Lee, Deokhoon Park, Jin Won Hyun. Myricetin Protects Cells against Oxidative Stress-Induced Apoptosis via Regulation of PI3K/Akt and MAPK Signaling Pathways. Int. J. Mol. Sci. 2010;11:4348-4360.
5. Paul Knekt, Jorma Kumpulainen, Ritva Järvinen, Harri Rissanen, Markku Heliövaara, Antti Reunanen, Timo Hakulinen, and Arpo Aromaa. Flavonoid intake and risk of chronic diseases. Am J Clin Nutr. 2002;76:560-8.
6. Grandjean EM, et al. Efficacy of oral long-term N-acetylcysteine in chronic, bronchopulmonary disease: a meta-analysis of published, double-blind placebo-controlled clinical trials. Clin Therapeut. 2000;22:209-21.
7. Kelly GS. Clinical Applications of N-acetylcysteine. Alt Med Rev. 1998;3(2):114-127.
8. Silva LA, Silveira PC, Pinho CA, Tuon T, Dal Pizzol F, Pinho RA. N-acetylcysteine supplementation and oxidative damage and inflammatory response after eccentric exercise. Int J Sport Nutr Exerc Metab. 2008 Aug;18(4):379-88.
9. Pashkow FJ, Watumull DG, Campbell CL. Astaxanthin: A Novel Potential Treatment for Oxidative Stress and Inflammation in Cardiovascular Disease. Am J Cardiol. 2008;101[suppl]:58D-68D.
10. Karppi J, Rissanen TH, Nyyssönen K, Kaikkonen J, Olsson AG, Voutilainen S, Salonen JT. Effects of astaxanthin supplementation on lipid peroxidation. Int J Vitam Nutr Res. 2007 Jan;77(1):3-11.
11. Sen CK, Khanna S, Roy S. Tocotrienol: The Natural Vitamin E to Defend the Nervous System? Ann. NY. Acad. Sci. 2004;1031:1-16.
12. Osakada F, Hashino A, Kumea T, Katsuki H, Kaneko S, Akaike A. a-Tocotrienol provides the most potent neuroprotection among vitamin E analogs on cultured striatal neurons. Neuropharmacology. 2004;47:904-915.
13. Chen TS Liou SY, Chan YL. Antioxidant Evaluation of Three Adaptogen Extracts. The American Journal of Chinese Medicine. 2008;36(6):1209-1217.
14. Peng CH, Su JD, Chyau CC, Sung TY, Ho SS, Peng CC, Peng RY Superritical Fluid Extracts of Rosemary Leaves Exhibit Potent Anti-Inflammation and Anti-Tumor Effects. Biosci. Biotechnol. Biochem. 2007;71(9):2223-2232.
15. Bakırel T, Bakırel U, Keles OU, Ülgen SG, Yardibi H. In vivo assessment of antidiabetic and antioxidant activities of rosemary (Rosmarinus officinalis) in alloxan-diabetic rabbits. Journal of Ethnopharmacology. 2008;116:64-73.
